SCHEMBL6847557

SCHEMBL6847557

C=C(C)C(=O)OCC(F)(OC(F)(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6847569 1.00 THRB (0.33) THRBTSHR
SCHEMBL15396988 0.95 THRB (0.34) THRBTSHR
SCHEMBL22251728 0.95 THRB (0.34) THRBTSHR
SCHEMBL6846368 0.95 THRB (0.34) THRBTSHR
SCHEMBL13612652 0.87 TSHR (0.37) THRBTSHR
SCHEMBL13024878 0.82 THRB (0.39) THRBTSHR
SCHEMBL24659534 0.81 THRB (0.33) THRB
SCHEMBL7712176 0.80
SCHEMBL8165284 0.80
SCHEMBL13024886 0.80 THRB (0.38) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040242822-A1 Copolymers containing fluorine, method for the production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-02 US disclosed