Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484679 | 0.89 | ABCG2 (0.50) | ABCG2ABCB1ABCC1PDE4BRAB9A | |
| SCHEMBL5483669 | 0.83 | ABCG2 (0.69) | ABCG2ABCB1ABCC1RAB9ANPC1 | |
| SCHEMBL5476447 | 0.79 | ABCG2 (0.60) | ABCG2ABCB1ABCC1NPC1TDP1 | |
| SCHEMBL6847669 | 0.77 | ABCG2 (0.49) | ABCG2ABCB1ABCC1RAB9ANPC1 | |
| SCHEMBL5482654 | 0.76 | MEN1 (0.46) | ABCG2ABCB1ABCC1PDE4BRAB9A | |
| SCHEMBL5483472 | 0.75 | KMT2A (0.46) | ABCG2ABCB1ABCC1RAB9ANPC1 | |
| SCHEMBL5482971 | 0.74 | KMT2A (0.48) | ABCG2ABCB1ABCC1RAB9ANPC1 | |
| SCHEMBL5486577 | 0.74 | MEN1 (0.44) | ABCG2ABCB1ABCC1RAB9ANPC1 | |
| SCHEMBL5486953 | 0.72 | ABCG2 (0.81) | ABCG2ABCB1ABCC1RAB9ANPC1 | |
| SCHEMBL5486371 | 0.71 | ABCG2 (0.78) | ABCG2ABCB1ABCC1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716851-B2 | ANTICANCER AGENTS | CYTOVIA, INC. | 2004-04-06 | — | — | US | claimed |