Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483669 | 0.83 | ABCG2 (0.69) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL5484679 | 0.79 | ABCG2 (0.50) | ABCG2ABCB1ABCC1TUBB4ATUBB | |
| SCHEMBL6847663 | 0.77 | ABCG2 (0.48) | ABCG2ABCB1ABCC1TUBB4ATUBB | |
| SCHEMBL5486953 | 0.73 | ABCG2 (0.81) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL5486371 | 0.72 | ABCG2 (0.78) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL16391835 | 0.72 | ABCG2 (0.68) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL27056360 | 0.69 | MEN1 (0.62) | MEN1KMT2AMAPTRAB9AKDM4E | |
| SCHEMBL5476447 | 0.69 | ABCG2 (0.60) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL5481520 | 0.69 | ESR1 (0.64) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL16392159 | 0.68 | ABCG2 (0.61) | ABCG2ABCB1ABCC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716851-B2 | ANTICANCER AGENTS | CYTOVIA, INC. | 2004-04-06 | — | — | US | claimed |