SCHEMBL6847672

SCHEMBL6847672

Oc1ccc2[nH]nnc2c1-c1ccccc1.Oc1ncnc(-c2ccccc2)n1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.34
PDGFRB P09619 1/20 0.34
GSK3A P49840 1/20 0.34
CDK9 P50750 1/20 0.34
CDK5 Q00535 1/20 0.34
ACVR1 Q04771 1/20 0.34
CDK5R1 Q15078 1/20 0.34
TAOK1 Q7L7X3 1/20 0.34
DYRK1B Q9Y463 1/20 0.34
ADORA2A P29274 1/20 0.32
GRIN2B Q13224 2/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
GYS1 P13807 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80394 0.84 CHEK1 (0.37) CSF1RGSK3ACDK5GRIN2BGRIN2D
SCHEMBL29359068 0.84 CHEK1 (0.37) CSF1RGSK3ACDK5GRIN2BGRIN2D
SCHEMBL6897857 0.83 CHEK1 (0.36) CSF1RGSK3ACDK5GRIN2BGRIN2D
SCHEMBL8836008 0.83 CHEK1 (0.36) CSF1RGSK3ACDK5GRIN2BGRIN2D
Benzotriazole SCHEMBL7192847 0.77 MAPT (0.33) CSF1RGSK3ACDK5GRIN2BGYS1
SCHEMBL45026 0.75 KMT2A (0.42) CSF1RPDGFRBGSK3ACDK9CDK5
SCHEMBL29595703 0.75 KMT2A (0.42) CSF1RPDGFRBGSK3ACDK9CDK5
SCHEMBL28715894 0.72 GSK3B (0.39) CDK5TAOK1
SCHEMBL28493025 0.72 MEN1 (0.44) CSF1RPDGFRBGSK3ACDK9CDK5
2,4-Dihydroxybenzophenone SCHEMBL10614014 0.70 MEN1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6767937-B2 A POLYMER PHASE HAVING MOLECULARLY DISPERSED THEREIN AN ACID SCAVENGER COMPOUND; A HINDERED AMINE LIGHT STABILIZER AND A HINDERED PHENOL ANTIOXIDANT COMPOUND ARE PRESENT AT A WEIGHT RATIO OF FROM 20:1 TO 1:20 EASTMAN KODAK COMPANY 2004-07-27 US disclosed