Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359068 | 0.80 | CHEK1 (0.37) | HTTCYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL80394 | 0.80 | CHEK1 (0.37) | HTTCYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL6897857 | 0.79 | CHEK1 (0.36) | HTTCYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL8836008 | 0.79 | CHEK1 (0.36) | HTTCYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL4614892 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AHPGDALDH1A1HTT | |
| 2,4-Dihydroxybenzophenone SCHEMBL1699129 | 0.74 | MEN1 (1.00) | MEN1KMT2AGAAUSP2KEAP1 | |
| 2,4-Dihydroxybenzophenone SCHEMBL39681 | 0.74 | MEN1 (1.00) | MEN1KMT2AGAAUSP2KEAP1 | |
| 2,4-Dihydroxybenzophenone SCHEMBL30201813 | 0.74 | MEN1 (1.00) | MEN1KMT2AGAAUSP2KEAP1 | |
| 2,4-Dihydroxybenzophenone SCHEMBL29351647 | 0.74 | MEN1 (1.00) | MEN1KMT2AGAAUSP2KEAP1 | |
| 2,4-Dihydroxybenzophenone SCHEMBL28108552 | 0.74 | MEN1 (1.00) | MEN1KMT2AGAAUSP2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4740450-A | COATING WITH PHOTOSENSITIVE LAYER CONTAINING SCRATCH IMPROVER; DRYING, MIGRATION | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1988-04-26 | — | — | US | disclosed |