Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855524 | 0.94 | FDPS (0.57) | FDPSMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6848311 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL6848310 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HPGDCA12 | |
| SCHEMBL6852966 | 0.84 | HCAR2 (0.51) | FDPSMAOBHCAR2KDM4EALDH1A1 | |
| SCHEMBL15669138 | 0.81 | FDPS (0.56) | FDPSMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12035658 | 0.81 | FDPS (0.56) | FDPSMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1884884 | 0.80 | ABCG2 (0.62) | FDPSMAOBALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL1884886 | 0.80 | ABCG2 (0.62) | FDPSMAOBALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL12036071 | 0.79 | FDPS (0.53) | FDPSMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30721745 | 0.78 | FDPS (0.53) | FDPSMAOBKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799827-B1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0799827-A1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |