Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848305 | 0.93 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL6852360 | 0.89 | TARBP2 (0.42) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL10792029 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL19621515 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL17934377 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL4486453 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL4467144 | 0.83 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL15502345 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL7402316 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD17B10LMNACA12 | |
| SCHEMBL6852355 | 0.81 | TARBP2 (0.46) | KDM4EALDH1A1HSD17B10LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799827-B1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0799827-A1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |