Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079645 | 0.92 | ALDH1A1 (0.41) | F10CYP2D6TSHRCYP3A4USP2 | |
| SCHEMBL6079034 | 0.84 | F10 (0.41) | F10CYP2D6TSHRCYP3A4USP2 | |
| SCHEMBL6078359 | 0.83 | ALDH1A1 (0.42) | F10CYP2D6TSHRCYP3A4USP2 | |
| SCHEMBL6079173 | 0.82 | F10 (0.46) | F10CYP2D6TSHRCYP3A4USP2 | |
| SCHEMBL6079085 | 0.79 | F10 (0.59) | F10CYP2D6TSHRCYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL6079680 | 0.78 | F10 (0.42) | F10TSHRALDH1A1KDM4E | |
| SCHEMBL6079366 | 0.78 | F10 (0.49) | F10CYP2D6TSHRCYP3A4USP2 | |
| SCHEMBL4522849 | 0.78 | F10 (0.58) | F10CYP2D6TSHRCYP3A4USP2 | |
| SCHEMBL6078825 | 0.77 | F10 (0.52) | F10TSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL6078643 | 0.77 | F10 (0.41) | F10TSHRALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191028-B1 | TRICYCLIC COMPOUNDS HAVING SPIRO UNION | MOCHIDA PHARM CO LTD (JP) | 2004-11-03 | — | — | EP | disclosed |