Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 5/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | LHCGR | P22888 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308896 | 0.78 | HHAT (0.63) | HHATCNR1LHCGRMAPK1NPSR1 | |
| SCHEMBL3365755 | 0.76 | HHAT (0.73) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL3367746 | 0.75 | HHAT (0.69) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL2306467 | 0.75 | HHAT (0.58) | HHATCNR1LHCGRMAPK1NPSR1 | |
| SCHEMBL21764028 | 0.75 | HHAT (1.00) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL3365878 | 0.74 | HHAT (0.67) | HHATCNR1LHCGR | |
| SCHEMBL3365448 | 0.73 | HHAT (0.66) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL2308216 | 0.73 | HHAT (0.59) | HHATCNR1LHCGR | |
| SCHEMBL2306201 | 0.73 | HHAT (0.56) | HHATCNR1LHCGRMAPK1NPSR1 | |
| SCHEMBL3366109 | 0.73 | HHAT (0.65) | HHATLHCGRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020849-A1 | CYTOHESIN INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) | 2011-02-24 | — | — | WO | disclosed |
| EP-2286808-A1 | Cytohesin inhibitors | Rheinische Friedrich-Wilhelms Universität (DE) | 2011-02-23 | — | — | EP | disclosed |