Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 15/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 15/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524292 | 0.91 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL7528558 | 0.90 | ADRA1A (0.58) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL6712339 | 0.88 | ADRA1A (0.55) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| Hydrochloric Acid SCHEMBL7971514 | 0.86 | MCHR1 (0.54) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL6713890 | 0.86 | ADRA1A (0.53) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL6710985 | 0.84 | ADRA1A (0.71) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| Hydrochloric Acid SCHEMBL6848930 | 0.84 | ADRA1A (0.70) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL6710986 | 0.83 | ADRA1A (0.72) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| SCHEMBL7528253 | 0.81 | ADRA1A (0.71) | ADRA1AADRA1DADRA1BMCHR1DRD2 | |
| Hydrochloric Acid SCHEMBL7526070 | 0.81 | ADRA1A (0.61) | ADRA1AADRA1DADRA1BMCHR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242609-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242609-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | MCHR1, MCHR2, MC4R | ADRA1A 161/4885ADRA1D 149/4885ADRA1B 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.