Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 12/20 | 0.56 |
| ▸ | TACR3 | P29371 | 17/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266946 | 0.88 | TACR2 (0.59) | TACR2TACR3KCNH2OPRM1TSHR | |
| SCHEMBL6853329 | 0.86 | TACR2 (0.57) | TACR2TACR3KCNH2OPRM1TSHR | |
| SCHEMBL6848956 | 0.85 | TACR2 (0.61) | TACR2TACR3KCNH2OPRM1TSHR | |
| SCHEMBL6851798 | 0.85 | TACR2 (0.61) | TACR2TACR3KCNH2OPRM1 | |
| SCHEMBL6852963 | 0.85 | TACR2 (0.61) | TACR2TACR3KCNH2OPRM1 | |
| SCHEMBL5420962 | 0.84 | TACR2 (0.55) | TACR2TACR3KCNH2OPRM1TSHR | |
| SCHEMBL6857861 | 0.84 | TACR2 (0.55) | TACR2TACR3KCNH2OPRM1TSHR | |
| SCHEMBL6853012 | 0.84 | TACR3 (0.64) | TACR2TACR3KCNH2OPRM1TSHR | |
| SCHEMBL5908692 | 0.84 | TACR2 (0.55) | TACR2TACR3KCNH2OPRM1TSHR | |
| SCHEMBL6851699 | 0.83 | TACR3 (0.67) | TACR2TACR3KCNH2OPRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780875-B2 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM S.P.A. (IT) | 2004-08-24 | — | — | US | claimed |
| US-6780875-B2 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM S.P.A. (IT) | 2004-08-24 | — | — | US | disclosed |