Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.59 |
| ▸ | MMP2 | P08253 | 5/20 | 0.59 |
| ▸ | MMP9 | P14780 | 5/20 | 0.59 |
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-P-Tolylcinnamamide SCHEMBL1603280 | 0.77 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| N-P-Tolylcinnamamide SCHEMBL4137542 | 0.77 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL11301842 | 0.73 | MMP1 (0.91) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL26120769 | 0.72 | MMP1 (0.88) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL13783551 | 0.71 | EGFR (0.54) | MMP1MMP2MMP9EGFRHDAC1 | |
| N-(4-Methoxyphenyl)Cinnamamide SCHEMBL4131114 | 0.71 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| N-(4-Methoxyphenyl)Cinnamamide SCHEMBL9094893 | 0.71 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| N-(4-Methoxyphenyl)Cinnamamide SCHEMBL4131112 | 0.71 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL24747889 | 0.70 | PTGS1 (0.69) | MAPTSMN1; SMN2MALT1NPC1RAB9A | |
| SCHEMBL13425358 | 0.70 | MMP1 (0.87) | MMP1MMP2MMP9EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020849-A1 | CYTOHESIN INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) | 2011-02-24 | — | — | WO | disclosed |
| EP-2286808-A1 | Cytohesin inhibitors | Rheinische Friedrich-Wilhelms Universität (DE) | 2011-02-23 | — | — | EP | disclosed |