Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689951 | 1.00 | SCN9A (0.48) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL6689639 | 1.00 | SCN9A (0.48) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL6689948 | 1.00 | SCN9A (0.48) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL18345004 | 0.91 | SCN9A (0.49) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL4436548 | 0.91 | SCN9A (0.49) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL4760197 | 0.91 | SCN9A (0.49) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL6694621 | 0.91 | SCN9A (0.49) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL5459736 | 0.91 | SCN9A (0.49) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL6694227 | 0.87 | SCN9A (0.47) | SCN9AMMP13GPR119TACR1MEN1 | |
| SCHEMBL6696975 | 0.87 | SCN9A (0.47) | SCN9AMMP13GPR119TACR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1384711-A1 | Optical resolution of a piperidine derivative | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-01-28 | — | — | EP | disclosed |