Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,6-Hexanediol SCHEMBL7029490 | 0.91 | CYP3A4 (0.39) | CYP3A4MIF | |
| SCHEMBL7857389 | 0.88 | — | — | |
| SCHEMBL28070263 | 0.85 | CYP3A4 (0.46) | CYP3A4MIF | |
| SCHEMBL3814088 | 0.83 | CYP3A4 (0.47) | CYP3A4MIF | |
| SCHEMBL9195080 | 0.77 | CYP3A4 (0.50) | CYP3A4 | |
| Alpha-Naphthylisocyanate SCHEMBL28223340 | 0.73 | CYP3A4 (0.45) | CYP3A4 | |
| SCHEMBL719741 | 0.71 | CYP3A4 (0.69) | CYP3A4MIF | |
| 1,5-Pentanediol SCHEMBL23530163 | 0.70 | MIF (0.58) | MIFMEN1KMT2A | |
| SCHEMBL4533760 | 0.70 | MIF (0.58) | MIFMEN1KMT2A | |
| SCHEMBL4528851 | 0.70 | MIF (0.58) | MIFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467976-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | AstraZeneca AB (SE) | 2004-10-20 | — | — | EP | disclosed |
| US-6734225-B2 | DISPERSION OF OIL-SOLUBLE DYE PARTICLES BASED ON A PYRAZOLO-(5,1-C)-S-TRIAZOLE OR PYRAZOLO(1,5-B) RING; STABILITY; COLORFASTNESS; WATERPROOFING; REPRODUCTION, ESPECIALLY MAGENTA; PRINTING ON PAPER; ANTIFOULING AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-05-11 | — | — | US | disclosed |
| WO-2003059893-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2003-07-24 | — | — | WO | disclosed |