Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 19/20 | 0.70 |
| ▸ | PRKACA | P17612 | 3/20 | 0.59 |
| ▸ | PRKACG | P22612 | 3/20 | 0.59 |
| ▸ | PRKACB | P22694 | 3/20 | 0.59 |
| ▸ | AKT2 | P31751 | 3/20 | 0.59 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.59 |
| ▸ | PRKCG | P05129 | 2/20 | 0.59 |
| ▸ | CDK1 | P06493 | 2/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.59 |
| ▸ | PIM1 | P11309 | 2/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857736 | 0.93 | AKT1 (0.71) | AKT1PRKACAPRKACGPRKACBAKT2 | |
| Ammonia Solution, Strong SCHEMBL6853385 | 0.89 | AKT1 (0.64) | AKT1PRKACAPRKACGPRKACBAKT2 | |
| SCHEMBL6849795 | 0.83 | AKT1 (0.85) | AKT1PRKACAPRKACGPRKACBAKT2 | |
| SCHEMBL6849748 | 0.83 | AKT1 (1.00) | AKT1PRKACAPRKACGPRKACBAKT2 | |
| SCHEMBL6855167 | 0.79 | AKT1 (1.00) | AKT1PRKACAPRKACGPRKACBAKT2 | |
| SCHEMBL6857809 | 0.78 | AKT1 (1.00) | AKT1AKT2AKT3PIM1GSK3A | |
| SCHEMBL6857813 | 0.78 | AKT1 (1.00) | AKT1AKT2AKT3PIM1GSK3A | |
| SCHEMBL7128961 | 0.78 | AKT1 (1.00) | AKT1AKT2AKT3PIM1GSK3A | |
| SCHEMBL6855409 | 0.78 | AKT1 (1.00) | AKT1PRKACAPRKACGPRKACBAKT2 | |
| SCHEMBL6855412 | 0.78 | AKT1 (1.00) | AKT1PRKACAPRKACGPRKACBAKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831175-B2 | Such as N,N-dimethyl-N-(2-((5-((E)-2-pyridin-4-ylvinyl) pyridin-3-yl)oxy)ethyl)amine | ABBOTT LABORATORIES | 2004-12-14 | — | — | US | claimed |