Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | FABP7 | O15540 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858226 | 1.00 | FABP5 (0.37) | FABP5F10FABP7MDM4TP53 | |
| SCHEMBL6858228 | 1.00 | FABP5 (0.37) | FABP5F10FABP7MDM4TP53 | |
| Succinic Acid SCHEMBL6855629 | 0.84 | KMT2A (0.38) | FABP5F10FABP7MDM4TP53 | |
| SCHEMBL8732800 | 0.81 | FABP5 (0.37) | FABP5FABP7MDM4TP53KMT2A | |
| Phosphonic Acid SCHEMBL6854647 | 0.80 | F10 (0.34) | FABP5F10FABP7MDM4TP53 | |
| SCHEMBL7926629 | 0.80 | KMT2A (0.46) | FABP5F10FABP7MDM4TP53 | |
| SCHEMBL6855032 | 0.80 | KMT2A (0.46) | FABP5F10FABP7MDM4TP53 | |
| Hypophosphorous Acid SCHEMBL7923595 | 0.79 | FABP5 (0.32) | FABP5F10FABP7MDM4TP53 | |
| SCHEMBL6855668 | 0.79 | FABP5 (0.37) | FABP5FABP7MDM4TP53KMT2A | |
| SCHEMBL6858060 | 0.79 | FABP5 (0.37) | FABP5FABP7MDM4TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828427-B1 | Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same | ISIS PHARMACEUTICALS, INC. | 2004-12-07 | — | — | US | disclosed |
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |