Sugi Predict

Sugi Predict / Compounds / Hypophosphorous Acid

Hypophosphorous Acid

Hypophosphorous Acid

SCHEMBL7923595

CCN(CC)CC.COC(OC)(OC(c1ccccc1)(c1ccccc1)c1ccccc1)[C@H]1CN(C(=O)OCC2c3ccccc3-c3ccccc32)C[C@@H]1C=O.O=[PH2]O.[H+]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FABP5 Q01469 2/20 0.32
▸ F10 P00742 1/20 0.32
▸ MDM4 O15151 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ FABP7 O15540 1/20 0.31
▸ BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphonic Acid SCHEMBL6854647 0.93 F10 (0.34) FABP5F10MDM4TP53FABP7
Succinic Acid SCHEMBL6855629 0.87 KMT2A (0.38) FABP5F10MDM4TP53FABP7
SCHEMBL6858228 0.79 FABP5 (0.37) FABP5F10MDM4TP53FABP7
SCHEMBL6849952 0.79 FABP5 (0.37) FABP5F10MDM4TP53FABP7
SCHEMBL6858226 0.79 FABP5 (0.37) FABP5F10MDM4TP53FABP7
SCHEMBL8732800 0.70 FABP5 (0.37) FABP5MDM4TP53FABP7BACE1
SCHEMBL6798554 0.70 FABP5 (0.37) FABP5F10MDM4TP53FABP7
SCHEMBL6796420 0.70 FABP5 (0.37) FABP5F10MDM4TP53FABP7
SCHEMBL8729229 0.70 LMNA (0.39) FABP5MDM4TP53FABP7
SCHEMBL8729183 0.70 LMNA (0.39) FABP5MDM4TP53FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184389-B1 FEATURE A PLURALITY OF FUNCTIONAL GROUPS ATTACHED TO BACKBONE AND PHOSPHORAMIDATE SITES ISIS PHARMACEUTICALS, INC. 2001-02-06 — — US disclosed