Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799195 | 0.71 | — | — | |
| SCHEMBL870972 | 0.68 | — | — | |
| SCHEMBL6850166 | 0.67 | — | — | |
| SCHEMBL5748917 | 0.65 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL15057332 | 0.64 | — | — | |
| SCHEMBL6850232 | 0.61 | — | — | |
| SCHEMBL6850246 | 0.60 | KDM4E (0.36) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL4570765 | 0.60 | KDM4E (0.47) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL3457997 | 0.58 | KDM4E (0.38) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL7146308 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036885-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2011-03-31 | — | — | WO | disclosed |