SCHEMBL4570765

SCHEMBL4570765

CC1CN2C=CC=CC2=N1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
POLB P06746 1/20 0.47
HSD17B10 Q99714 1/20 0.47
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21759296 0.76 KDM4E (0.44) KDM4EALDH1A1HPGDPOLBHSD17B10
SCHEMBL15128276 0.73 KDM4E (0.53) KDM4EALDH1A1HPGDGAA
SCHEMBL15128270 0.72 KDM4E (0.34) KDM4EALDH1A1HPGDGAA
SCHEMBL13698339 0.72 KDM4E (0.44) KDM4EALDH1A1HPGDPOLBHSD17B10
SCHEMBL15128273 0.71 KDM4E (0.51) KDM4EALDH1A1HPGD
SCHEMBL15128256 0.69 KDM4E (0.33) KDM4EALDH1A1HPGDGAA
SCHEMBL6418003 0.69 ALDH1A1 (0.41) KDM4EALDH1A1HPGDPOLBHSD17B10
SCHEMBL14468266 0.69 KDM4E (0.32) KDM4EALDH1A1POLBGAA
SCHEMBL15128272 0.69 KDM4E (0.36) KDM4EALDH1A1HPGD
SCHEMBL15128264 0.69 KDM4E (0.33) KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-8216696-B2 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-10 US disclosed
US-20120119196-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 US disclosed
US-8049411-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-11-01 US disclosed
US-7768195-B2 Organic electroluminescent device with improved luminous efficiency IDEMITSU KOSAN CO., LTD. (JP) 2010-08-03 US disclosed
US-20090309488-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-12-17 US disclosed
US-20090174313-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC-ELECTROLUMINESCENCE-MATERIAL-CONTAINING SOLUTION IDEMITSU KOSAN CO., LTD. (JP) 2009-07-09 US disclosed
US-20090153041-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-06-18 US disclosed
EP-2067778-A1 Quinoxaline derivative, and light emitting element, licht emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-06-10 EP disclosed
US-20070273270-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090153041-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device and Electronic Appliance Using the Same SLC1A2, SLC18A2, SLC18A3 KDM4E 258/4885ALDH1A1 1610/4885HPGD 2143/4885
US-20090309488-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EPCAM, ILK, PPOX KDM4E 2903/4885ALDH1A1 1810/4885HPGD 2793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.