Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TTK | P33981 | 4/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5075042 | 0.87 | LRRK2 (0.46) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL7918987 | 0.82 | HPGD (0.55) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL8550890 | 0.79 | ATM (0.55) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL1253994 | 0.78 | NOS1 (0.50) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL4008191 | 0.77 | HPGD (0.62) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL1172817 | 0.76 | NOS1 (0.49) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL837904 | 0.76 | GAA (0.53) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL1172395 | 0.76 | NOS1 (0.49) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL1172797 | 0.76 | NOS1 (0.49) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL1171722 | 0.76 | NOS1 (0.50) | MAPTHPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058720-A2 | COMPOUND LIBRARIES OF 1,3,5-SUBSTITUTE INDAZOLE DERIVATIVES AS COMPOUNDS FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO THE G-PROTEIN COUPLED RECEPTOR | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | claimed |
| WO-2004058720-A2 | COMPOUND LIBRARIES OF 1,3,5-SUBSTITUTE INDAZOLE DERIVATIVES AS COMPOUNDS FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO THE G-PROTEIN COUPLED RECEPTOR | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | disclosed |