Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.72 |
| ▸ | CA2 | P00918 | 17/20 | 0.72 |
| ▸ | CA4 | P22748 | 5/20 | 0.72 |
| ▸ | CA7 | P43166 | 5/20 | 0.72 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CA11 | O75493 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974838 | 0.83 | CA1 (0.78) | CA1CA2CA4CA7CA9 | |
| SCHEMBL14316971 | 0.83 | CA1 (0.78) | CA1CA2CA4CA7CA9 | |
| SCHEMBL9795960 | 0.82 | CA2 (1.00) | CA1CA2CA4CA7CA9 | |
| SCHEMBL13739962 | 0.81 | CA2 (0.74) | CA1CA2CA4CA7CA9 | |
| SCHEMBL22118522 | 0.80 | CA1 (0.72) | CA1CA2CA4CA7CA9 | |
| SCHEMBL6850079 | 0.80 | CA1 (0.72) | CA1CA2CA4CA7CA9 | |
| SCHEMBL14315047 | 0.80 | CA1 (0.76) | CA1CA2CA4CA7CA9 | |
| SCHEMBL7482494 | 0.77 | CA1 (0.55) | CA1CA2CA4CA7CA9 | |
| SCHEMBL21558901 | 0.76 | CA1 (0.67) | CA1CA2CA4CA7CA9 | |
| SCHEMBL6850255 | 0.75 | CA1 (0.69) | CA1CA2CA4CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-20020123468-A1 | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123468-A1 | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease | CES1, CYP51A1, SPINT2 | CA1 695/4885CA2 869/4885CA4 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.