Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852482 | 0.82 | LMNA (0.37) | ERN1DYRK1ADYRK1B | |
| SCHEMBL6847782 | 0.75 | CYP3A4 (0.36) | — | |
| SCHEMBL6852143 | 0.74 | CLK4 (0.30) | — | |
| SCHEMBL15820746 | 0.72 | ERN1 (0.43) | ERN1DYRK1ADYRK1B | |
| SCHEMBL6852255 | 0.71 | CYP2A6 (0.37) | ERN1 | |
| SCHEMBL6852643 | 0.69 | ATM (0.42) | ERN1 | |
| SCHEMBL6854136 | 0.60 | DYRK1A (0.58) | DYRK1ADYRK1B | |
| SCHEMBL2814958 | 0.60 | ATM (0.65) | ERN1 | |
| SCHEMBL6847768 | 0.59 | CYP2A6 (0.56) | DYRK1ADYRK1B | |
| SCHEMBL6854124 | 0.59 | HDAC3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |