Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 17/20 | 0.44 |
| ▸ | DRD2 | P14416 | 16/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.44 |
| ▸ | HRH1 | P35367 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD5 | P21918 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 11/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12504742 | 0.92 | HTR2A (0.42) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL12505640 | 0.89 | HTR2A (0.43) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL6853039 | 0.86 | HTR2A (0.58) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL1958487 | 0.78 | HTR2A (0.73) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL12296697 | 0.76 | HTR2C (0.41) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL6881873 | 0.74 | DRD2 (0.72) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL1961482 | 0.74 | DRD2 (0.72) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL6881948 | 0.74 | DRD2 (0.71) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL6885578 | 0.74 | DRD2 (0.71) | HTR2ADRD2HTR2CKCNH2ADRA1A | |
| SCHEMBL15489540 | 0.72 | HTR2A (0.63) | HTR2ADRD2HTR2CKCNH2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067220-A1 | A PROCESS FOR THE PURIFICATION OF PALIPERIDONE | CHEMO IBÉRICA, S.A. (ES) | 2011-06-09 | — | — | WO | disclosed |