Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780208 | 0.98 | CA1 (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL15244128 | 0.80 | FGFR4 (0.33) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL15244480 | 0.80 | KDM4E (0.30) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7186613 | 0.79 | CA12 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5174970 | 0.79 | CA12 (0.34) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL778583 | 0.77 | CA1 (0.41) | MMP9CA12CA1CA2CA7 | |
| SCHEMBL776497 | 0.76 | CA12 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15725726 | 0.75 | — | — | |
| SCHEMBL15725738 | 0.75 | PTGS2 (0.33) | TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL16140144 | 0.75 | CA1 (0.40) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014125499-A1 | IMPROVED AND COMMERCIALLY VIABLE PROCESS FOR THE PREPARATION OF HIGH PURE PLERIXAFOR BASE | NATCO PHARMA LIMITED (IN) | 2014-08-21 | — | — | WO | disclosed |
| WO-2014125499-A1 | IMPROVED AND COMMERCIALLY VIABLE PROCESS FOR THE PREPARATION OF HIGH PURE PLERIXAFOR BASE | NATCO PHARMA LIMITED (IN) | 2014-08-21 | — | — | WO | disclosed |
| EP-0619813-B1 | LINKED CYCLIC POLYAMINES WITH ACTIVITY AGAINST HIV | ANORMED INC (CA) | 2004-08-18 | — | — | EP | disclosed |