Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851857 | 1.00 | RARB (0.44) | RARBPLA2G2ATP53TSHRPLA2G4B | |
| SCHEMBL6850260 | 1.00 | RARB (0.44) | RARBPLA2G2ATP53TSHRPLA2G4B | |
| SCHEMBL6847498 | 1.00 | RARB (0.44) | RARBPLA2G2ATP53TSHRPLA2G4B | |
| SCHEMBL6851460 | 0.91 | RARB (0.41) | RARBTP53TSHRPLA2G4BPDE3B | |
| SCHEMBL6851520 | 0.91 | PLA2G4B (0.44) | RARBTP53TSHRPLA2G4BPDE3B | |
| SCHEMBL6847323 | 0.91 | PLA2G4B (0.44) | RARBTP53TSHRPLA2G4BPDE3B | |
| SCHEMBL6851875 | 0.91 | PLA2G4B (0.44) | RARBTP53TSHRPLA2G4BPDE3B | |
| SCHEMBL6847239 | 0.91 | RARB (0.41) | RARBTP53TSHRPLA2G4BPDE3B | |
| SCHEMBL6850190 | 0.91 | RARB (0.41) | RARBTP53TSHRPLA2G4BPDE3B | |
| SCHEMBL6850231 | 0.91 | RARB (0.41) | RARBTP53TSHRPLA2G4BPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-B1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LTD (GB) | 2004-11-24 | — | — | EP | disclosed |
| US-6630128-B1 | Insoluble support | DESTINY PHARMA LIMITED (GB) | 2003-10-07 | — | — | US | disclosed |
| EP-1107971-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | Destiny Pharma Limited (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012512-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |