Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847323 | 1.00 | PLA2G4B (0.44) | PLA2G4BPTPN11RARBSMPD1PDE3B | |
| SCHEMBL6851520 | 1.00 | PLA2G4B (0.44) | PLA2G4BPTPN11RARBSMPD1PDE3B | |
| SCHEMBL6847498 | 0.91 | RARB (0.44) | PLA2G4BPTPN11RARBPDE3BPDE3A | |
| SCHEMBL6851385 | 0.91 | RARB (0.44) | PLA2G4BPTPN11RARBPDE3BPDE3A | |
| SCHEMBL6850260 | 0.91 | RARB (0.44) | PLA2G4BPTPN11RARBPDE3BPDE3A | |
| SCHEMBL6851857 | 0.91 | RARB (0.44) | PLA2G4BPTPN11RARBPDE3BPDE3A | |
| SCHEMBL6851411 | 0.88 | PLA2G4B (0.42) | PLA2G4BPTPN11RARBSMPD1CYP1A2 | |
| SCHEMBL6851528 | 0.88 | PLA2G4B (0.42) | PLA2G4BPTPN11RARBSMPD1CYP1A2 | |
| SCHEMBL6851858 | 0.88 | PLA2G4B (0.42) | PLA2G4BPTPN11RARBSMPD1CYP1A2 | |
| SCHEMBL584885 | 0.86 | TSHR (0.50) | PLA2G4BPTPN11SMPD1CYP1A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-B1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LTD (GB) | 2004-11-24 | — | — | EP | disclosed |
| US-6630128-B1 | Insoluble support | DESTINY PHARMA LIMITED (GB) | 2003-10-07 | — | — | US | disclosed |