SCHEMBL6851854

SCHEMBL6851854

NCC(=O)NS(=O)(=O)c1ccccc1F

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.54
KAT6A Q92794 10/20 0.53
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
TSHR P16473 1/20 0.44
CDK1 P06493 1/20 0.42
CDK2 P24941 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16739378 0.81 MEN1 (0.55) GBA1KAT6AMEN1KMT2ATSHR
SCHEMBL29489599 0.81 MEN1 (0.55) GBA1KAT6AMEN1KMT2ATSHR
SCHEMBL3973365 0.79 EGFR (0.55) GBA1KAT6AMEN1KMT2ACA1
SCHEMBL27176171 0.79 KAT6A (0.58) GBA1KAT6AMEN1KMT2ATSHR
SCHEMBL6848738 0.78 CA1 (0.60) MEN1KMT2ACA1CA2
SCHEMBL5551864 0.78 CA2 (0.45) KAT6ACA1CA2CDK1CDK2
SCHEMBL28282283 0.77 KAT6A (0.53) GBA1KAT6AMEN1KMT2ATSHR
SCHEMBL21667704 0.77 MEN1 (0.46) GBA1KAT6AMEN1KMT2ATSHR
SCHEMBL3973361 0.77 EGFR (0.52) GBA1KAT6AMEN1KMT2A
SCHEMBL3928657 0.75 CA1 (0.67) KAT6AMEN1KMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6774212-B2 FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT BRISTOL-MYERS SQUIBB PHARMA COMPANY 2004-08-10 US disclosed