SCHEMBL6851909

SCHEMBL6851909

CCCC(C)c1ccc(C=CC(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.65
MAPK1 P28482 1/20 0.65
SMN1; SMN2 Q16637 3/20 0.51
NPC1 O15118 2/20 0.51
POLB P06746 1/20 0.51
RAB9A P51151 1/20 0.51
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
ESR1 P03372 4/20 0.49
ESR2 Q92731 3/20 0.49
HCAR2 Q8TDS4 2/20 0.49
CA12 O43570 1/20 0.49
AKR1B10 O60218 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA3 P07451 1/20 0.49
PKM P14618 1/20 0.49
TYR P14679 1/20 0.49
AKR1B1 P15121 1/20 0.49
CA4 P22748 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18713537 0.87 KDM4E (0.69) KDM4EMAPK1SMN1; SMN2NPC1POLB
SCHEMBL20125118 0.84 SMN1; SMN2 (0.57) SMN1; SMN2NPC1POLBRAB9AALDH1A1
SCHEMBL10903828 0.84 KDM4E (0.60) KDM4EMAPK1SMN1; SMN2NPC1POLB
SCHEMBL21164580 0.83 KDM4E (0.58) KDM4EMAPK1SMN1; SMN2NPC1POLB
SCHEMBL17288968 0.81 KDM4E (0.65) KDM4EMAPK1SMN1; SMN2NPC1POLB
SCHEMBL819055 0.79 KDM4E (1.00) KDM4EMAPK1SMN1; SMN2NPC1POLB
SCHEMBL1711780 0.79 KDM4E (1.00) KDM4EMAPK1SMN1; SMN2NPC1POLB
SCHEMBL20824863 0.79 APP (0.59) SMN1; SMN2ALDH1A1LMNAESR1HCAR2
SCHEMBL20032085 0.78 KDM4E (0.66) KDM4EMAPK1SMN1; SMN2NPC1POLB
SCHEMBL28223266 0.78 KDM4E (0.66) KDM4EMAPK1SMN1; SMN2NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104109538-B Aligning agent for liquid crystal, liquid crystal orientation film, liquid crystal display cells, phase retardation film and its manufacture method, polymer and compound JSR株式会社 2018-01-16 CN disclosed
CN-103571501-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display device, and manufacturing method for the liquid crystal alignment film JSR株式会社 2017-05-24 CN disclosed
CN-103450479-B Crystal aligning agent, liquid crystal orienting film and liquid crystal display cells JSR CO., LTD. (JP) 2016-11-30 CN disclosed
CN-105602580-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element CHI MEI CORP 2016-05-25 CN disclosed
US-20040067001-A1 Ultra-thin polarization mode converters based on liquid crystal materials INTEL CORPORATION 2004-04-08 US disclosed
US-4941992-A FERROELECTRIC OPTICAL APPARATUS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1990-07-17 US disclosed
EP-0241502-B1 N-SUBSTITUTED AMINO ACID DERIVATIVES FOR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1990-05-23 EP disclosed
EP-0156726-B1 PROCESS FOR THE PREPARATION OF A SMECTIC C-CHIRAL FERROELECTRIC LIQUID CRYSTAL, LIQUID CRYSTAL AND DISPLAY DEVICE USING THE SAME. THOMSON-CSF (FR) 1988-01-13 EP disclosed
EP-0241502-A1 N-SUBSTITUTED AMINO ACID DERIVATIVES FOR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES. SECR DEFENCE BRIT (GB) 1987-10-21 EP disclosed
WO-1987002375-A1 N-SUBSTITUTED AMINO ACID DERIVATIVES FOR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1987-04-23 WO disclosed
EP-0156726-A1 Process for the preparation of a smectic C-chiral ferroelectric liquid crystal, liquid crystal and display device using the same. THOMSON-CSF (FR) 1985-10-02 EP disclosed