SCHEMBL819055

SCHEMBL819055

CC(C)c1ccc(C=CC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
MAPK1 P28482 1/20 1.00
SMN1; SMN2 Q16637 5/20 0.65
NPC1 O15118 4/20 0.65
RAB9A P51151 4/20 0.65
POLB P06746 1/20 0.65
HCAR2 Q8TDS4 2/20 0.59
TYR P14679 2/20 0.59
PKM P14618 2/20 0.59
CA12 O43570 1/20 0.59
AKR1B10 O60218 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
ESR1 P03372 1/20 0.59
CA3 P07451 1/20 0.59
AKR1B1 P15121 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
DPP4 P27487 1/20 0.59
CA5A P35218 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711780 1.00 KDM4E (1.00) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL11683046 0.86 KDM4E (0.76) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL11253542 0.86 KDM4E (0.75) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL11253548 0.86 KDM4E (0.75) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
Cinnamic Acid SCHEMBL10932316 0.85 KDM4E (0.73) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
Cinnamic Acid SCHEMBL10932313 0.85 KDM4E (0.73) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL7140088 0.85 KDM4E (0.73) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL12814412 0.85 KDM4E (0.73) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL4322158 0.85 KDM4E (0.73) KDM4EMAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL28002416 0.85 KDM4E (0.73) KDM4EMAPK1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449900-B Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer 浙江奥首材料科技有限公司 2023-11-21 CN claimed
CN-114163313-B Method for selectively synthesizing EZ-stilbene by coupling ruthenium-catalyzed aryl diazonium salt with cinnamic acid 中山大学 2023-11-03 CN claimed
CN-115449900-A Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer 浙江奥首材料科技有限公司 2022-12-09 CN claimed
CN-114163313-A Method for selectively synthesizing EZ-stilbene by coupling aryl diazonium salt and cinnamic acid under catalysis of ruthenium 中山大学 2022-03-11 CN claimed
EP-2967038-B1 METHODS, COMPOUNDS AND COMPOSITIONS FOR REPELLING INSECTS AND ARACHNIDS NATIONAL CENTER FOR SCIENT RESEARCH DEMOKRITOS (GR) 2019-05-08 EP claimed
EP-1429768-B1 NOVEL MEDICAMENTS FOR INHALATION BOEHRINGER INGELHEIM PHARMA (DE) 2016-11-16 EP claimed
US-20160029643-A1 Methods, Compounds and Compositions for Repelling Insects and/or Arachnids NATIONAL CENTER FOR SCIENTIFIC RESEARCH "DEMOKRITOS" (GB) 2016-02-04 US claimed
EP-2967038-A2 METHODS, COMPOUNDS AND COMPOSITIONS FOR REPELLING INSECTS AND ARACHNIDS NATIONAL CENTER FOR SCIENTIFIC RESEARCH "DEMOKRITOS" (GR) 2016-01-20 EP claimed
WO-2014140314-A2 METHODS, COMPOUNDS AND COMPOSITIONS FOR REPELLING INSECTS AND/OR ARACHNIDS UNIVERSITE DE NEUCHATEL (CH) 2014-09-18 WO claimed
US-20070093558-A1 Electrostatic aerosol compositions RECKITT BENCKISER (UK) LIMITED, A UK CORPORATION 2007-04-26 US claimed
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
US-20050256149-A1 Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-11-17 US claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
US-6919325-B2 Respiratory system disorders; synergistic mixtures BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-07-19 US claimed
EP-1409605-A2 ELECTROSTATIC AEROSOL COMPOSITIONS Reckitt Benckiser (U.K.) LIMITED (GB) 2004-04-21 EP claimed
US-20030130300-A1 Respiratory system disorders; synergistic mixtures BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-10 US claimed
US-20030096878-A1 Electrostatic aerosol compositions RECKITT BENCKISER (UK) LIMITED 2003-05-22 US claimed
WO-2001018145-A2 ELECTROSTATIC AEROSOL COMPOSITIONS RECKITT BENCKISER (UK) LIMITED (GB) 2001-03-15 WO claimed
US-5961875-A Antifreeze/coolant composition containing cinnamic acid CCI CO., LTD. (JP) 1999-10-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256149-A1 Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts ADRB3, ADRB1, HSD3B1 KDM4E 4185/4885MAPK1 2552/4885SMN1; SMN2 1739/4885
US-20160029643-A1 Methods, Compounds and Compositions for Repelling Insects and/or Arachnids ACHE, NISCH, BCHE KDM4E 2793/4885MAPK1 3792/4885SMN1; SMN2 2488/4885
US-20030130300-A1 Respiratory system disorders; synergistic mixtures ADRB3, ADRB1, CHRM3 KDM4E 4788/4885MAPK1 2904/4885SMN1; SMN2 1191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.