Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853361 | 0.87 | CA12 (0.44) | CA12CA1CA9RXFP1CYP17A1 | |
| SCHEMBL10192915 | 0.84 | CA12 (0.44) | CA12CA1CA9RXFP1CYP17A1 | |
| SCHEMBL1771858 | 0.81 | IDO1 (0.47) | RXFP1 | |
| SCHEMBL13055401 | 0.79 | CA12 (0.49) | CA12CA1CA9RXFP1CYP17A1 | |
| SCHEMBL4612314 | 0.78 | CA12 (0.48) | CA12CA1CA9RXFP1CYP17A1 | |
| SCHEMBL3783697 | 0.78 | CA12 (0.48) | CA12CA1CA9RXFP1CYP17A1 | |
| SCHEMBL27284495 | 0.77 | CYP17A1 (0.49) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL27284560 | 0.77 | CYP17A1 (0.49) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL3781384 | 0.77 | CA12 (0.47) | CA12CA1CA9RXFP1CYP17A1 | |
| SCHEMBL3295634 | 0.76 | HPGD (0.43) | CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800097-B2 | FOR DYEING KERATIN FIBERS; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-05 | — | — | US | disclosed |
| US-6780998-B2 | DEVELOPER-COUPLER SUBSTANCE COMBINATION HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-24 | — | — | US | disclosed |
| US-20030070241-A1 | Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-04-17 | — | — | US | disclosed |
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-12-19 | — | — | US | disclosed |
| US-6436152-B1 | Substituted 2-aminoalky-1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, CYP1B1, ALDH7A1 | CA12 1530/4885CA1 1545/4885CA9 1583/4885 |
| US-20030070241-A1 | Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, ALDH7A1, DDC | CA12 1314/4885CA1 1357/4885CA9 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.