Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.79 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.56 |
| ▸ | ITGAL | P20701 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187848 | 0.89 | PDE7A (1.00) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL1149093 | 0.85 | PDE7A (0.85) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL5253210 | 0.81 | PDE7A (0.79) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL3033239 | 0.81 | PDE7A (0.72) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL7605532 | 0.81 | ITGB2 (0.59) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL7187676 | 0.80 | ITGB2 (0.80) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL7606216 | 0.80 | PDE7A (0.76) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL7192598 | 0.79 | PDE7A (0.73) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL720839 | 0.79 | PDE7A (0.73) | PDE7AITGB2ICAM1ITGALMAPT | |
| SCHEMBL18561704 | 0.78 | MAPT (0.51) | PDE7AITGB2ICAM1ITGALMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | claimed |
| US-5763481-A | PESTICIDES; INSECTICIDES, MITICIDES | NOVARTIS CORPROATION (US) | 1998-06-09 | — | — | US | disclosed |