Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.44 |
| ▸ | PPP5C | P53041 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692609 | 0.80 | GBA1 (0.46) | GBA1EPHX2 | |
| SCHEMBL6361896 | 0.79 | GBA1 (0.39) | GBA1PPP5CSMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL15470821 | 0.79 | GBA1 (0.48) | GBA1PPP5CEPHX2 | |
| SCHEMBL14210158 | 0.77 | GBA1 (0.53) | GBA1PPP5CEPHX2 | |
| SCHEMBL14538764 | 0.76 | GBA1 (0.37) | GBA1PPP5CSMN1; SMN2 | |
| SCHEMBL9033090 | 0.76 | GBA1 (0.37) | GBA1PPP5CSMN1; SMN2 | |
| SCHEMBL6852785 | 0.76 | PPP5C (0.54) | GBA1PPP5CSMN1; SMN2 | |
| SCHEMBL19549635 | 0.76 | GBA1 (0.46) | GBA1 | |
| SCHEMBL19549582 | 0.76 | GBA1 (0.46) | GBA1PPP5CEPHX2 | |
| SCHEMBL533902 | 0.76 | GBA1 (0.50) | GBA1PPP5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073492-A1 | DERIVATIVES OF AMINOCYCLITOLS, OBTAINMENT PROCEDURE AND USES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2011-06-23 | — | — | WO | disclosed |