SCHEMBL533902

SCHEMBL533902

CCCCCCCCCCCCCCCCCCOC1CC(CO)CC(OCCCCCCCCCCCCCCCCCC)C1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 6/20 0.50
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
GJB2 P29033 1/20 0.36
LPAR2 Q9HBW0 3/20 0.35
LPAR3 Q9UBY5 3/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
PPP5C P53041 1/20 0.34
GBA2 Q9HCG7 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470821 0.86 GBA1 (0.48) GBA1PPP5C
SCHEMBL13165909 0.83 GBA1 (0.46) GBA1PPP5C
SCHEMBL19549635 0.83 GBA1 (0.46) GBA1HTTGJB2CA1CA2
SCHEMBL19549582 0.83 GBA1 (0.46) GBA1LPAR2LPAR3PPP5C
SCHEMBL2017266 0.77 GBA1 (0.47) GBA1PPP5C
SCHEMBL19549609 0.76 GBA1 (0.40) GBA1PPP5C
SCHEMBL19549572 0.76 GBA1 (0.40) GBA1
SCHEMBL19549575 0.76 GBA1 (0.40) GBA1GJB2
SCHEMBL22346083 0.76 GBA1 (0.40) GBA1
SCHEMBL19684689 0.76 GBA1 (0.46) GBA1MEN1THRBHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12351601-B2 Method for producing peptide continuously AJINOMOTO CO., INC. (JP) 2025-07-08 US claimed
US-12351601-B2 Method for producing peptide continuously AJINOMOTO CO., INC. (JP) 2025-07-08 US disclosed
US-9670121-B2 Diphenylmethane compound AJINOMOTO CO., INC. (JP) 2017-06-06 US disclosed
US-20160060198-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC. (JP) 2016-03-03 US disclosed
US-9206230-B2 Benzylic compound AJINOMOTO CO., INC. (JP) 2015-12-08 US disclosed
US-9169187-B2 Method of making peptides using diphenylmethane compound AJINOMOTO CO., INC. (JP) 2015-10-27 US disclosed
US-9029504-B2 Fluorene compound AJINOMOTO CO., INC. (JP) 2015-05-12 US disclosed
US-20140371424-A1 BENZYLIC COMPOUND AJINOMOTO CO., INC. (JP) 2014-12-18 US disclosed
US-8859732-B2 Benzylic compound AJINOMOTO CO., INC. (JP) 2014-10-14 US disclosed
US-20140213761-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC (JP) 2014-07-31 US disclosed
US-8722934-B2 Diphenylmethane compound AJINOMOTO CO., INC. (JP) 2014-05-13 US disclosed
US-20140046022-A1 FLUORENE COMPOUND AJINOMOTO CO., INC. (JP) 2014-02-13 US disclosed
US-8569453-B2 Fluorene compound AJINOMOTO CO., INC. (JP) 2013-10-29 US disclosed
EP-2518041-A1 BENZYL COMPOUND Ajinomoto Co., Inc. (JP) 2012-10-31 EP disclosed
EP-2415745-A1 DIPHENYLMETHANE COMPOUND Ajinomoto Co., Inc. (JP) 2012-02-08 EP disclosed
EP-2415744-A1 FLUORENE COMPOUND Ajinomoto Co., Inc. (JP) 2012-02-08 EP disclosed
US-20110160433-A1 BENZYLIC COMPOUND AJINOMOTO CO., INC. (JP) 2011-06-30 US disclosed
US-20100249374-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC. (JP) 2010-09-30 US disclosed
US-20100240867-A1 FLUORENE COMPOUND AJINOMOTO CO. INC. (JP) 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249374-A1 DIPHENYLMETHANE COMPOUND CCKAR, DNPEP, QPCTL GBA1 4187/4885MEN1 1909/4885THRB 1826/4885
US-20110160433-A1 BENZYLIC COMPOUND VIP, NGLY1, FURIN GBA1 844/4885MEN1 109/4885THRB 3133/4885
US-20140213761-A1 DIPHENYLMETHANE COMPOUND CCKAR, VIP, CCKBR GBA1 4023/4885MEN1 1386/4885THRB 1988/4885
US-20140046022-A1 FLUORENE COMPOUND NPPA, FURIN, SFPQ GBA1 777/4885MEN1 115/4885THRB 2854/4885
US-20160060198-A1 DIPHENYLMETHANE COMPOUND CCKAR, VIP, CCKBR GBA1 4023/4885MEN1 1386/4885THRB 1988/4885
US-20140371424-A1 BENZYLIC COMPOUND VIP, NGLY1, FURIN GBA1 844/4885MEN1 109/4885THRB 3133/4885
US-20100240867-A1 FLUORENE COMPOUND NPPA, FURIN, SFPQ GBA1 777/4885MEN1 115/4885THRB 2854/4885
US-12351601-B2 Method for producing peptide continuously VIP, NPPA, NGLY1 GBA1 3272/4885MEN1 1477/4885THRB 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.