Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860895 | 0.91 | ADORA2A (0.72) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859817 | 0.89 | ADORA2A (0.78) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6852845 | 0.87 | ADORA2A (0.66) | ADORA2AADORA1ADORA2BNPC1RAB9A | |
| SCHEMBL6216214 | 0.86 | ADORA2A (0.79) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859424 | 0.85 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BNPC1RAB9A | |
| SCHEMBL6216365 | 0.85 | ADORA2A (0.78) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6214350 | 0.84 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6213678 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6215001 | 0.80 | ADORA2A (0.81) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6215875 | 0.80 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |