Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859372 | 0.92 | ADORA2A (0.69) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859424 | 0.91 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BMEN1NPC1 | |
| SCHEMBL6216214 | 0.88 | ADORA2A (0.79) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6852764 | 0.87 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BNPC1RAB9A | |
| SCHEMBL6859817 | 0.83 | ADORA2A (0.78) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6216365 | 0.83 | ADORA2A (0.78) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6212498 | 0.83 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6214350 | 0.82 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6216827 | 0.82 | ADORA2A (0.67) | ADORA2AADORA1ADORA2BNPC1RAB9A | |
| SCHEMBL2581885 | 0.81 | ADORA2A (0.79) | ADORA2AADORA1ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |