Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869326 | 0.91 | ADORA2A (0.76) | ADORA2AADORA2BADORA3ADORA1ALOX15 | |
| SCHEMBL25437252 | 0.83 | ADORA2A (0.79) | ADORA2AADORA2BADORA3ADORA1ALOX15 | |
| SCHEMBL12103714 | 0.82 | ADORA2A (0.85) | ADORA2AADORA2BADORA3ADORA1ALOX15 | |
| SCHEMBL6708382 | 0.82 | ADORA2A (0.63) | ADORA2AADORA2BADORA3ADORA1ALOX15 | |
| SCHEMBL5490949 | 0.80 | ADORA2A (0.73) | ADORA2AADORA2BADORA3ADORA1ALOX15 | |
| SCHEMBL10585659 | 0.78 | ADORA2A (0.78) | ADORA2AADORA2B | |
| SCHEMBL10588301 | 0.78 | ADORA2A (0.75) | ADORA2AADORA2B | |
| SCHEMBL10586444 | 0.78 | ADORA2A (0.82) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10588074 | 0.77 | ADORA2A (0.82) | ADORA2AADORA2B | |
| SCHEMBL9762726 | 0.77 | ADORA2A (0.87) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996453-B1 | METHODS FOR THE INHIBITION OF NEURONAL ACTIVITY BY LOCAL DELIVERY OF ADENOSINE | MOHLER HANNS (CH) | 2004-04-28 | — | — | EP | claimed |