Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.76 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25437252 | 0.93 | ADORA2A (0.79) | ADORA2AADORA2BKDM4EADORA3ADORA1 | |
| SCHEMBL6708382 | 0.91 | ADORA2A (0.63) | ADORA2AADORA2BKDM4EADORA3ADORA1 | |
| SCHEMBL6852905 | 0.91 | ADORA2A (0.62) | ADORA2AADORA2BADORA3ADORA1ALOX15 | |
| SCHEMBL9762945 | 0.87 | ADORA2A (1.00) | ADORA2AADORA2BKDM4EADORA3ADORA1 | |
| SCHEMBL10588368 | 0.87 | ADORA2A (1.00) | ADORA2AADORA2BKDM4EADORA3ADORA1 | |
| SCHEMBL5490949 | 0.86 | ADORA2A (0.73) | ADORA2AADORA2BKDM4EADORA3ADORA1 | |
| Hydrochloric Acid SCHEMBL9762842 | 0.86 | ADORA2A (0.98) | ADORA2AADORA2BKDM4EADORA3ADORA1 | |
| SCHEMBL22533842 | 0.85 | ADORA2A (0.72) | ADORA2AADORA2BKDM4EADORA3ADORA1 | |
| Hydrochloric Acid SCHEMBL23859924 | 0.85 | ADORA2A (0.71) | ADORA2AADORA2BKDM4EADORA3ADORA1 | |
| SCHEMBL12102216 | 0.83 | ADORA2A (0.82) | ADORA2AADORA2BKDM4EADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825174-B2 | MIXTURE OF SURFACTANT AND NUCLEIC ACIDS | EAST CAROLINA UNIVERSITY | 2004-11-30 | — | — | US | disclosed |