Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859788 | 0.91 | ADORA2A (0.74) | ADORA2AADORA1ADORA2BADORA3 | |
| Hydrochloric Acid SCHEMBL6860959 | 0.90 | ADORA2A (0.73) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6852899 | 0.86 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6212561 | 0.81 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859798 | 0.80 | ADORA2A (0.68) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859709 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6852766 | 0.76 | ADORA2A (0.70) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2563509 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| Hydrochloric Acid SCHEMBL6860873 | 0.75 | ADORA2A (0.74) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6213678 | 0.74 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |