Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852899 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859788 | 0.80 | ADORA2A (0.74) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6852910 | 0.80 | ADORA2A (0.74) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6212561 | 0.79 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| Hydrochloric Acid SCHEMBL6860959 | 0.79 | ADORA2A (0.73) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6215875 | 0.78 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859505 | 0.77 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859709 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6213079 | 0.75 | ADORA2A (0.70) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2563509 | 0.74 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |