Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852969 | 0.83 | CNR1 (0.48) | KMT2AHDAC1GAAMEN1KDM4E | |
| SCHEMBL30694971 | 0.79 | P2RX4 (0.49) | KMT2AP2RX4ALDH1A1MEN1KDM4E | |
| SCHEMBL17038835 | 0.79 | P2RX4 (0.49) | KMT2AP2RX4ALDH1A1MEN1KDM4E | |
| SCHEMBL958473 | 0.79 | CNR1 (0.58) | ALDH1A1KDM4EMAPTGFERCNR1 | |
| SCHEMBL17039004 | 0.78 | TDP1 (0.50) | KMT2AALDH1A1GAAMEN1MAPT | |
| SCHEMBL29459606 | 0.78 | TDP1 (0.50) | KMT2AALDH1A1GAAMEN1MAPT | |
| SCHEMBL1863037 | 0.77 | KMT2A (0.61) | KMT2AP2RX4ALDH1A1GAAMEN1 | |
| SCHEMBL6850492 | 0.77 | HDAC1 (0.50) | KMT2AHDAC1P2RX4ALDH1A1GAA | |
| SCHEMBL17039042 | 0.76 | CYP2D6 (0.48) | HDAC1ALDH1A1KDM4EMAPTGFER | |
| SCHEMBL18937376 | 0.76 | CNR1 (0.46) | HDAC1ALDH1A1KDM4EMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058720-A2 | COMPOUND LIBRARIES OF 1,3,5-SUBSTITUTE INDAZOLE DERIVATIVES AS COMPOUNDS FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO THE G-PROTEIN COUPLED RECEPTOR | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | disclosed |