Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852970 | 0.83 | KMT2A (0.49) | CNR1HDAC1KMT2AMEN1GAA | |
| SCHEMBL3775553 | 0.82 | PTGER4 (0.60) | CNR1PTGER4PARP1ELANECYP2D6 | |
| SCHEMBL31647277 | 0.82 | PTGER4 (0.60) | CNR1PTGER4PARP1ELANECYP2D6 | |
| SCHEMBL24273625 | 0.81 | PTGER4 (0.62) | CNR1PTGER4KMT2APARP1MEN1 | |
| SCHEMBL8877216 | 0.79 | ELANE (0.55) | CNR1PARP1ELANE | |
| SCHEMBL13671617 | 0.79 | CNR1 (0.50) | CNR1PTGER4PARP1ELANECYP2D6 | |
| SCHEMBL8591344 | 0.78 | PTGER4 (0.52) | CNR1HDAC1PTGER4KMT2AELANE | |
| SCHEMBL6114223 | 0.78 | PTGER4 (0.57) | CNR1HDAC1PTGER4KMT2AMEN1 | |
| SCHEMBL31647362 | 0.78 | PTGER4 (0.58) | CNR1HDAC1PTGER4ELANECYP2D6 | |
| SCHEMBL29459642 | 0.77 | PTGER4 (0.49) | CNR1PTGER4PARP1ELANECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058720-A2 | COMPOUND LIBRARIES OF 1,3,5-SUBSTITUTE INDAZOLE DERIVATIVES AS COMPOUNDS FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO THE G-PROTEIN COUPLED RECEPTOR | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | disclosed |