Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL5664831 | 1.00 | ALOX15 (0.44) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Glutamine SCHEMBL27660739 | 0.98 | KMT2A (0.46) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Glutamine SCHEMBL4667538 | 0.98 | KMT2A (0.46) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Glutamine SCHEMBL5663861 | 0.96 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Glutamine SCHEMBL5665046 | 0.95 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Glutamine SCHEMBL6377469 | 0.95 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Valine SCHEMBL5666569 | 0.94 | ALOX15 (0.37) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Valine SCHEMBL5663868 | 0.94 | ALOX15 (0.37) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Glutamine SCHEMBL17782941 | 0.94 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2AGRM8 | |
| Glutamine SCHEMBL17907437 | 0.94 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2AGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794362-B1 | TOPICAL COSMETIC APPLIED AS EMULSION, LOTION, SPRAY, POWDER, OINTMENT, CREAM, INCREASES SKIN'S TURGOR | CONNECTIVE TISSUE IMAGINEERING LLC | 2004-09-21 | — | — | US | disclosed |