Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 15/20 | 0.53 |
| ▸ | TACR2 | P21452 | 6/20 | 0.53 |
| ▸ | TACR3 | P29371 | 6/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6848750 | 0.99 | TRPV4 (0.53) | TRPV4TACR2TACR3OPRM1KCNH2 | |
| SCHEMBL6349526 | 0.91 | TRPV4 (0.53) | TRPV4TACR2TACR3OPRM1 | |
| Hydrochloric Acid SCHEMBL5945393 | 0.90 | TRPV4 (0.53) | TRPV4TACR2TACR3OPRM1KCNH2 | |
| Bromide SCHEMBL5945395 | 0.90 | TRPV4 (0.53) | TRPV4TACR2TACR3OPRM1 | |
| SCHEMBL5945427 | 0.84 | TRPV4 (0.56) | TRPV4TACR2TACR3OPRM1KCNH2 | |
| SCHEMBL2373330 | 0.83 | TRPV4 (0.72) | TRPV4TACR2TACR3OPRM1KCNH2 | |
| SCHEMBL5945416 | 0.83 | TRPV4 (0.62) | TRPV4TACR2TACR3OPRM1KCNH2 | |
| SCHEMBL6851721 | 0.83 | TRPV4 (0.53) | TRPV4TACR2TACR3OPRM1KCNH2 | |
| SCHEMBL6853291 | 0.83 | TRPV4 (0.55) | TRPV4TACR2TACR3OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL5733490 | 0.82 | TRPV4 (0.71) | TRPV4TACR2TACR3OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780875-B2 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM S.P.A. (IT) | 2004-08-24 | — | — | US | claimed |