Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 18/20 | 0.74 |
| ▸ | TACR3 | P29371 | 17/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.71 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855970 | 0.90 | TACR2 (0.75) | TACR2TACR3OPRM1TRPV4 | |
| SCHEMBL5437389 | 0.85 | TACR2 (0.84) | TACR2TACR3OPRM1TRPV4 | |
| SCHEMBL5467567 | 0.85 | TACR2 (0.84) | TACR2TACR3OPRM1TRPV4 | |
| SCHEMBL5461434 | 0.84 | TACR2 (0.83) | TACR2TACR3OPRM1TRPV4 | |
| SCHEMBL28773316 | 0.84 | TACR2 (0.85) | TACR2TACR3OPRM1TRPV4 | |
| SCHEMBL6851786 | 0.84 | TACR3 (0.52) | TACR2TACR3OPRM1 | |
| SCHEMBL6851791 | 0.84 | TACR3 (0.52) | TACR2TACR3OPRM1 | |
| SCHEMBL6853032 | 0.84 | TACR2 (0.79) | TACR2TACR3OPRM1TRPV4 | |
| SCHEMBL6851688 | 0.83 | TACR2 (0.84) | TACR2TACR3OPRM1TRPV4 | |
| SCHEMBL5467406 | 0.83 | TACR2 (0.81) | TACR2TACR3OPRM1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780875-B2 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM S.P.A. (IT) | 2004-08-24 | — | — | US | disclosed |