Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 19/20 | 0.52 |
| ▸ | TACR2 | P21452 | 14/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851791 | 1.00 | TACR3 (0.52) | TACR3TACR2OPRM1KCNH2 | |
| SCHEMBL6857817 | 0.85 | TACR3 (0.50) | TACR3TACR2OPRM1KCNH2 | |
| SCHEMBL6857894 | 0.85 | TACR2 (0.51) | TACR3TACR2OPRM1KCNH2 | |
| SCHEMBL6857895 | 0.85 | TACR2 (0.51) | TACR3TACR2OPRM1KCNH2 | |
| SCHEMBL6853285 | 0.84 | TACR2 (0.74) | TACR3TACR2OPRM1 | |
| SCHEMBL6852983 | 0.82 | TACR2 (0.56) | TACR3TACR2OPRM1KCNH2 | |
| SCHEMBL6851699 | 0.81 | TACR3 (0.67) | TACR3TACR2OPRM1KCNH2 | |
| SCHEMBL5909007 | 0.80 | TACR2 (0.55) | TACR3TACR2OPRM1KCNH2 | |
| SCHEMBL6853618 | 0.80 | TACR2 (0.55) | TACR3TACR2OPRM1KCNH2 | |
| SCHEMBL7238544 | 0.79 | TACR3 (0.51) | TACR3TACR2OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780875-B2 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM S.P.A. (IT) | 2004-08-24 | — | — | US | claimed |