Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853483 | 0.83 | PDE7A (0.48) | MMP2MMP9CHRM2ADORA3KCNH2 | |
| SCHEMBL8471852 | 0.83 | PDE7A (0.48) | MMP2MMP9CHRM2ADORA3KCNH2 | |
| SCHEMBL1408090 | 0.83 | PDE7A (0.48) | MMP2MMP9CHRM2ADORA3KCNH2 | |
| SCHEMBL5483163 | 0.74 | CHRM2 (0.62) | MMP2MMP9CHRM2ADORA3KCNH2 | |
| SCHEMBL21939542 | 0.70 | AKR1B1 (0.46) | MMP2MMP9KCNH2CA12CA1 | |
| SCHEMBL19605042 | 0.70 | AKR1B1 (0.46) | MMP2MMP9KCNH2CA12CA1 | |
| SCHEMBL10131744 | 0.69 | LMNA (0.51) | MMP2MMP9KCNH2AKR1B1HTR6 | |
| SCHEMBL10116540 | 0.69 | PDK2 (0.55) | — | |
| SCHEMBL31238681 | 0.69 | PDK2 (0.55) | — | |
| SCHEMBL21940203 | 0.69 | PDE7A (0.50) | AKR1B1GAAHTR6PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745785-B1 | Pharmaceutical composition for preventing or treating cerebral oedema | BIOCODEX (FR) | 2011-03-09 | — | — | EP | disclosed |