Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539003 | 0.92 | TMEM97 (0.37) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL13013398 | 0.92 | TMEM97 (0.37) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL10703049 | 0.92 | TMEM97 (0.37) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL6855778 | 0.89 | HPSE (0.34) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL13868581 | 0.85 | HPSE (0.39) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL16950173 | 0.85 | TMEM97 (0.38) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL16950251 | 0.84 | TMEM97 (0.32) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL17068337 | 0.84 | TMEM97 (0.36) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL17068318 | 0.84 | TMEM97 (0.36) | TMEM97SIGMAR1HPSETP53OPRM1 | |
| SCHEMBL886854 | 0.83 | TMEM97 (0.38) | TMEM97SIGMAR1HPSETP53OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780888-B1 | FAT-SOLUBLE AND STABLE SILICON-CONTAINING DERIVATIVES OF ASCORBIC ACID | L'OREAL S.A. (FR) | 2004-08-24 | — | — | US | disclosed |
| EP-1228075-B1 | SILICON COMPOUNDS DERIVED FROM ASCORBIC ACID | OREAL (FR) | 2003-06-18 | — | — | EP | disclosed |
| EP-1228075-A1 | SILICON COMPOUNDS DERIVED FROM ASCORBIC ACID | L'OREAL (FR) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001030784-A1 | SILICON COMPOUNDS DERIVED FROM ASCORBIC ACID | L'OREAL (FR) | 2001-05-03 | — | — | WO | disclosed |