SCHEMBL6855778

SCHEMBL6855778

CC1(C)OCC(C2OC(=O)C(OCCC[Si](C)(C)C)=C2OCc2ccccc2)O1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPSE Q9Y251 1/20 0.34
MAOB P27338 1/20 0.33
TMEM97 Q5BJF2 2/20 0.32
SIGMAR1 Q99720 2/20 0.32
PRKCA P17252 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
TP53 P04637 2/20 0.31
ACACB O00763 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8539003 0.89 TMEM97 (0.37) HPSEMAOBTMEM97SIGMAR1OPRM1
SCHEMBL10703049 0.89 TMEM97 (0.37) HPSEMAOBTMEM97SIGMAR1OPRM1
SCHEMBL13013398 0.89 TMEM97 (0.37) HPSEMAOBTMEM97SIGMAR1OPRM1
SCHEMBL13868581 0.89 HPSE (0.39) HPSEMAOBTMEM97SIGMAR1PRKCA
SCHEMBL6853632 0.89 TMEM97 (0.36) HPSEMAOBTMEM97SIGMAR1OPRM1
SCHEMBL16950173 0.82 TMEM97 (0.38) HPSEMAOBTMEM97SIGMAR1PRKCA
SCHEMBL16950251 0.82 TMEM97 (0.32) HPSEMAOBTMEM97SIGMAR1OPRM1
SCHEMBL17068337 0.82 TMEM97 (0.36) HPSEMAOBTMEM97SIGMAR1OPRM1
SCHEMBL17068318 0.82 TMEM97 (0.36) HPSEMAOBTMEM97SIGMAR1OPRM1
SCHEMBL886854 0.81 TMEM97 (0.38) HPSEMAOBTMEM97SIGMAR1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8217665-A None JP disclosed
WO-2020135999-A1 ANTIMICROBIAL MIXTURE CONTAINING 4-(3-ETHOXY-4-HYDROXYPHENYL)BUTAN-2-ONE AND AN AMMONIUM COMPOUND, AND COMPOSITION CONTAINING SAME L'OREAL (FR) 2020-07-02 WO disclosed
US-6784281-B2 ADDING A PROTEASE HAVING AN EXOPEPTIDASE ACTIVITY TO A NATURAL RUBBER LATEX AND AGING THE LATEX SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2004-08-31 US disclosed
US-6780888-B1 FAT-SOLUBLE AND STABLE SILICON-CONTAINING DERIVATIVES OF ASCORBIC ACID L'OREAL S.A. (FR) 2004-08-24 US disclosed
US-6660818-B2 Method for producing a fluoropolymer ASAHI GLASS COMPANY, LIMITED (JP) 2003-12-09 US disclosed
EP-1228075-B1 SILICON COMPOUNDS DERIVED FROM ASCORBIC ACID OREAL (FR) 2003-06-18 EP disclosed
CN-1414967-A Silicon compounds derived from ascorbic acid, preparation method, composition containing the compounds and application OREAL (FR) 2003-04-30 CN disclosed
US-20030060664-A1 Method for producing a fluoropolymer ASAHI GLASS COMPANY, LIMITED (JP) 2003-03-27 US disclosed
US-6462159-B1 PREPARED USING A PROTEOLYTIC ENZYME AND ONE OR MORE SURFACTANTS SELECTED FROM CATIONIC AND NONIONIC SURFACTANTS AND WHICH CONTAINS BOTH CATIONIC AND NONIONIC SURFACTANTS AFTER THE TREATMENT SUMITOMO RUBBER INDUSTRIES, LTD (JP) 2002-10-08 US disclosed
EP-1228075-A1 SILICON COMPOUNDS DERIVED FROM ASCORBIC ACID L'OREAL (FR) 2002-08-07 EP disclosed
US-20020091232-A1 Method of preparing low allergic natural rubber latex and deproteinized natural rubber latex, and low allergic natural rubber and deproteinized natural rubber KAO CORPORATION (JP) 2002-07-11 US disclosed
US-6265479-B1 MIXTURE OF PROPTEOLYTIC ENZYME AND CATIONIC SURFACTANT SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
WO-2001030784-A1 SILICON COMPOUNDS DERIVED FROM ASCORBIC ACID L'OREAL (FR) 2001-05-03 WO disclosed
JP-H08217665-A BATHING AGENT COMPOSITION EARTH CHEM CORP LTD 1996-08-27 JP disclosed
EP-0184787-B1 CYANIDE-FREE HEMOGLOBIN REAGENT TECHNICON INSTRUMENTS CORPORATION(a Delaware corporation) (US) 1991-04-03 EP disclosed
EP-0184787-A2 Cyanide-free hemoglobin reagent TECHNICON INSTRUMENTS CORPORATION(a Delaware corporation) (US) 1986-06-18 EP disclosed