Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487972 | 0.92 | PTGDR2 (0.47) | PTGDR2MEN1KMT2ANPSR1 | |
| SCHEMBL6484031 | 0.91 | PTGDR2 (0.47) | PTGDR2MEN1KMT2ANPSR1 | |
| SCHEMBL6495252 | 0.90 | PTGDR2 (0.49) | PTGDR2MEN1KMT2ANPSR1 | |
| SCHEMBL6487502 | 0.87 | MEN1 (0.47) | PTGDR2MEN1KMT2ANPSR1 | |
| SCHEMBL6492696 | 0.85 | PTGDR2 (0.47) | PTGDR2MEN1KMT2ANPSR1 | |
| SCHEMBL6493912 | 0.84 | MEN1 (0.47) | PTGDR2MEN1KMT2ANPSR1 | |
| SCHEMBL6502517 | 0.83 | PTGDR2 (0.46) | PTGDR2MEN1KMT2ANPSR1 | |
| SCHEMBL6490814 | 0.82 | MEN1 (0.47) | PTGDR2MEN1KMT2ANPSR1 | |
| SCHEMBL6852208 | 0.81 | HTR2A (0.31) | PTGDR2 | |
| SCHEMBL6483800 | 0.81 | MEN1 (0.47) | PTGDR2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173440-B1 | TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS | UPJOHN CO (US) | 2004-09-15 | — | — | EP | claimed |