Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483143 | 0.76 | HTR6 (0.42) | HTR6HTR2CMEN1KMT2AGAA | |
| SCHEMBL6487941 | 0.72 | HTR6 (0.44) | HTR6HTR2CMEN1KMT2AHTR2A | |
| SCHEMBL6495114 | 0.71 | HTR2C (0.48) | HTR6HTR2CMEN1KMT2AHTR2A | |
| SCHEMBL6496653 | 0.68 | HTR2C (0.42) | HTR6HTR2CMEN1KMT2AHTR2A | |
| SCHEMBL6482987 | 0.67 | HTR2C (0.41) | HTR6HTR2CMEN1KMT2AHTR2A | |
| SCHEMBL6496160 | 0.65 | HTR2C (0.56) | HTR6HTR2CMEN1KMT2AHTR2A | |
| SCHEMBL6484359 | 0.65 | HTR2C (0.51) | HTR6HTR2CMEN1KMT2AHTR2A | |
| SCHEMBL6495834 | 0.64 | HTR2C (0.43) | HTR6HTR2CMEN1KMT2AHTR2A | |
| SCHEMBL6509113 | 0.64 | HTR2C (0.45) | HTR6HTR2CMEN1KMT2AHTR2A | |
| SCHEMBL6482718 | 0.64 | SLC6A4 (0.44) | HTR6HTR2CMEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173440-B1 | TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS | UPJOHN CO (US) | 2004-09-15 | — | — | EP | claimed |